Publications

2023 

Hossan MS, Lin ES, Riedl E, Stram A, Mehlhaff E, Koeppel L, Warner J, Uko I, Mankowski Gettle L, Lubner S, McGregor SM, Zhang W, Murphy W, Kratz JD. Spatial Alignment of Organoids Tracking Subclonal Chemotherapy Resistance in Pancreatic and Ampullary Cancer. Bioengineering (Basel). 2023 Jan 10;10(1). doi: 10.3390/bioengineering10010091. PubMed PMID: 36671664; PubMed Central PMCID: PMC9854538.

Agarwal PD, Lucey MR, Said A, Kratz J. Immunotherapy for HCC: limitations in patients with NASH. Ann Hepatol. 2023 Mar-Apr;28(2):100886. doi: 10.1016/j.aohep.2022.100886. PubMed PMID: 36925208.

2022 

Patel MA, Kratz JD, Lubner SJ, Loconte NK, Uboha NV. Esophagogastric Cancers: Integrating Immunotherapy Therapy Into Current Practice. J Clin Oncol. 2022 Aug 20;40(24):2751-2762. doi: 10.1200/JCO.21.02500. Epub 2022 Jul 15. Review. PubMed PMID: 35839430.

Skala MC, Deming DA, Kratz JD. Technologies to Assess Drug Response and Heterogeneity in Patient-Derived Cancer Organoids. Annu Rev Biomed Eng. 2022 Jun 6;24:157-177. doi: 10.1146/annurev-bioeng-110220-123503. Epub 2022 Mar 8. Review. PubMed PMID: 35259932; PubMed Central PMCID: PMC9177801.

DeStefanis RA, Kratz JD, Olson AM, Sunil A, DeZeeuw AK, Gillette AA, Sha GC, Johnson KA, Pasch CA, Clipson L, Skala MC, Deming DA. Impact of baseline culture conditions of cancer organoids when determining therapeutic response and tumor heterogeneity. Sci Rep. 2022 Mar 25;12(1):5205. doi: 10.1038/s41598-022-08937-z. PubMed PMID: 35338174; PubMed Central PMCID: PMC8956720.

2020 

Shah SI, D’Angelo CR, Kratz JD, Yang DT. Diagnostic challenges in an aggressive case of peripheralizing marginal zone lymphoma. Clin Case Rep. 2020 Dec;8(12):3303-3310. doi: 10.1002/ccr3.3395. eCollection 2020 Dec. PubMed PMID: 33363923; PubMed Central PMCID: PMC7752602.

Kratz JD, LoConte NK. Defining Early Multidisciplinary Goals: NEXTO Trial in High-Risk Colorectal Cancer with Liver Metastases. Ann Surg Oncol. 2020 Oct;27(11):4075-4078. doi: 10.1245/s10434-020-08629-w. Epub 2020 May 22. PubMed PMID: 32444912.

Johnson KA, DeStefanis RA, Emmerich PB, Grogan PT, Kratz JD, Makkar SK, Clipson L, Deming DA. Human Colon Organoids and Other Laboratory Strategies to Enhance Patient Treatment Selection. Curr Treat Options Oncol. 2020 Apr 23;21(5):35. doi: 10.1007/s11864-020-00737-9. Review. PubMed PMID: 32328818; PubMed Central PMCID: PMC7924903.

2019 

Kratz JD, Deming DA. The evolving treatment paradigm for BRAF V600 mutant colorectal cancer. Ann Transl Med. 2019 Dec;7(Suppl 8):S257. doi: 10.21037/atm.2019.12.61. PubMed PMID: 32015976; PubMed Central PMCID: PMC6976492.

DeStefanis RA, Kratz JD, Emmerich PB, Deming DA. Targeted Therapy in Metastatic Colorectal Cancer: Current Standards and Novel Agents in Review. Curr Colorectal Cancer Rep. 2019 Apr;15(2):61-69. doi: 10.1007/s11888-019-00430-6. Epub 2019 Mar 20. PubMed PMID: 31130830; PubMed Central PMCID: PMC6528813.

Fricke SL, Payne SN, Favreau PF, Kratz JD, Pasch CA, Foley TM, Yueh AE, Van De Hey DR, Depke MG, Korkos DP, Sha GC, DeStefanis RA, Clipson L, Burkard ME, Lemmon KK, Parsons BM, Kenny PA, Matkowskyj KA, Newton MA, Skala MC, Deming DA. MTORC1/2 Inhibition as a Therapeutic Strategy for PIK3CA Mutant Cancers. Mol Cancer Ther. 2019 Feb;18(2):346-355. doi: 10.1158/1535-7163.MCT-18-0510. Epub 2018 Nov 13. PubMed PMID: 30425131; PubMed Central PMCID: PMC6363831.

2018 

Kratz JD, Uboha NV, Lubner SJ, Mulkerin DL, Clipson L, Yi Y, Yu M, Matkowskyj KA, LoConte NK, Deming DA. Metastatic Bulk Independently Predicts Outcomes for EGFR Precision Targeting in Colorectal Cancer. J Natl Compr Canc Netw. 2018 Dec;16(12):1442-1450. doi: 10.6004/jnccn.2018.7074. PubMed PMID: 30545991.

2016 

Kratz JD, El-Shazly AY, Mambuque SG, Demetria E, Veldkamp P, Anderson TS. Gynaecomastia in two men on stable antiretroviral therapy who commenced treatment for tuberculosis. Malawi Med J. 2016 Dec;28(4):185-187. doi: 10.4314/mmj.v28i4.8. PubMed PMID: 28321284; PubMed Central PMCID: PMC5348613.

Sievers CK, Kratz JD, Zurbriggen LD, LoConte NK, Lubner SJ, Uboha N, Mulkerin D, Matkowskyj KA, Deming DA. The Multidisciplinary Management of Colorectal Cancer: Present and Future Paradigms. Clin Colon Rectal Surg. 2016 Sep;29(3):232-8. doi: 10.1055/s-0036-1584292. Review. PubMed PMID: 27582648; PubMed Central PMCID: PMC4991962.

Kratz JD, Turk AA, Sievers CK, Clipson L, Matkowskyj KA, Deming DA. Molecular Profiles Guide Colorectal Cancer Treatment. Fed Pract. 2016 May;33(Suppl 4):50S-53S. PubMed PMID: 30766219; PubMed Central PMCID: PMC6375446.

Kratz JD, Chaddha A, Bhattacharjee S, Goonewardena SN. Atherosclerosis and Nanotechnology: Diagnostic and Therapeutic Applications. Cardiovasc Drugs Ther. 2016 Feb;30(1):33-9. doi: 10.1007/s10557-016-6649-2. Review. PubMed PMID: 26809711; PubMed Central PMCID: PMC4791194.

2013 

Goonewardena SN, Kratz JD, Zong H, Desai AM, Tang S, Emery S, Baker JR Jr, Huang B. Design considerations for PAMAM dendrimer therapeutics. Bioorg Med Chem Lett. 2013 May 15;23(10):2872-5. doi: 10.1016/j.bmcl.2013.03.088. Epub 2013 Apr 1. PubMed PMID: 23583511.

2011 

Stelzer AC, Frank AT, Kratz JD, Swanson MD, Gonzalez-Hernandez MJ, Lee J, Andricioaei I, Markovitz DM, Al-Hashimi HM. Discovery of selective bioactive small molecules by targeting an RNA dynamic ensemble. Nat Chem Biol. 2011 Jun 26;7(8):553-9. doi: 10.1038/nchembio.596. PubMed PMID: 21706033; PubMed Central PMCID: PMC3319144.

2010 

Stelzer AC, Kratz JD, Zhang Q, Al-Hashimi HM. RNA dynamics by design: biasing ensembles towards the ligand-bound state. Angew Chem Int Ed Engl. 2010 Aug 2;49(33):5731-3. doi: 10.1002/anie.201000814. PubMed PMID: 20583015; PubMed Central PMCID: PMC3319304.