Publications

2025 

Kratz JD, Rehman S, Johnson KA, Gillette AA, Sunil A, Favreau PF, Pasch CA, Miller D, Zarling LC, Yeung AH, Clipson L, Anderson SJ, DeZeeuw AK, Sprackling CM, Lemmon KK, Abbott DE, Burkard ME, Bassetti MF, Eickhoff JC, Foley EF, Heise CP, Kimple RJ, Lawson EH, LoConte NK, Lubner SJ, Mulkerin DL, Matkowskyj KA, Sanger CB, Uboha NV, Mcilwain SJ, Ong IM, Carchman EH, Skala MC, Deming DA. “Subclonal response heterogeneity to define cancer organoid sensitivity.” Scientific Reports 2025, 15(1), 12072. PMID: 40200028. 

Basree, MM, Witt JS, Uboha NV, Lubner M, Minter R, Weber S, Ronnekleiv-Kelly S, Abbot D, Kratz JD, Patel M, Zafar SN, LoConte N, Lubner SJ, Deming DA, Ritter MA, Mohindra P, Bassetti MF. Neoadjuvant SBRT plus Elective Nodal Irradiation with Concurrent Capecitabine for Patients with Resectable Pancreatic Cancer: Survival Analysis of a Prospective Phase 1 Trial. Practical Radiation Oncology, 2025 (In Press). PMID: 39924052. 

Uboha NV, Basree MM, Eickhoff JC, Deming DA, Matkowskyj K, Maloney J, McCarthy D, DeCamp M, LoConte N, Emmerich PB, Kraus S, Patel MA, Kratz JD, Lubner SJ, Hurst N, Bassetti MF. “Phase I/II Trial of Perioperative Avelumab in Combination With Chemoradiation in the Treatment of Stage II/III Resectable Esophageal and Gastroesophageal Junction Cancer.” Journal of Surgical Oncology, 2025 (In Press). PMID: 39757733. 

 

2024 

DeZeeuw AK, Bassetti MF, Carchman EH, Heise CP, Hayden D, Lawson EH, Sanger CB, King R, LoConte NK, Lubner SJ, Kratz JD, Deming DA. “Carboplatin and Paclitaxel Chemoradiation for Localized Anal Cancer in Patients Not Eligible for Mitomycin and 5-Fluorouracil.” Cancers, 2024 16 (17), 3062. PMID: 39272920. 

Patel MA, Kratz JD, Carlson AS, Ascencio YO, Kelley BS, LoConte NK. “Molecular Targets and Therapies for Ampullary Cancer.” Journal of the National Comprehensive Cancer Network, 2024. PMID: 38181507. 

Marcinak CT, Schwartz PB, Basre MM, Hurst N, Bassetti M, Kratz JD, Uboha NV. “Treatment of Oligometastatic GI Cancers.” ASCO Educational Book, 2024 44 (1): e430152. PMID: 38190577 

Marcinak CT, Ahmed KS, LoConte NK, Praska CE, Varley PR, Weber SM, Abbott DE, Ronnekleiv-Kelly SM, Kratz JD, Lubner SJ, Minter RM, Zefar SN. “Understanding futility in pancreaticoduodenectomy: Insights from a national cohort.” Journal of Surgical Oncology, 2024. PMID: 39082628 

 

2023 

Hossan MS, Lin ES, Riedl E, Stram A, …, Murphy W, Kratz JD. Spatial Alignment of Organoids Tracking Subclonal Chemotherapy Resistance in Pancreatic and Ampullary Cancer. Bioengineering 2023, 10(1), 91. PMID: 36671664. 

Agarwal PD, Lucey MR, Said A, Kratz JD. “Immunotherapy for HCC: Limitations in patients with NASH.” Annals of Hepatology. 2023 28(2): 100886. PMID: 36925208. 

Kratz JD, Uboha NV. “Combination Immunotherapy in Gastrointestinal Cancer.” touchREVIEWS in Oncology & Haematology, 2023. 

Skala ML, Deming DA, Kratz JD. “Technologies to Assess Drug Response and Heterogeneity in Patient-Derived Cancer Organoids.” Annual Reviews of Biomedical Engineering, 2022. PMID: 35259932.  

Patel MA, Kratz JD, Lubner SJ, LoConte NK, Uboha NV. “Esophagogastric Cancers: Integrating Immunotherapy Therapy Into Current Practice.” Journal of Clinical Oncology, 2022. PMID: 35839430 

 

2022 

DeStefanis RA*, Kratz JD*, Olson AM*, Sunil A, DeZeeuw AK, Gillette AA, Sha GC, Johnson KA, Pasch CA, Clipson L, Skala MC, Deming DA. “Impact of baseline culture conditions of mouse-derived cancer organoids when determining therapeutic response and tumor heterogeneity.” Scientific Reports, 2022 12(1): 1-4. PMID: 35338174 

Kratz JD, Zhang W, Patel MA, Uboha NV. “Challenges in Biomarker-Based Clinical Trials for Patients with Gastrointestinal Malignancies.” Expert Review of Precision Medicine and Drug Development, 2022 

 

2020 

Johnson KA, DeStefanis RA, Emmerich PB, Grogan PT, Kratz JD, Makkar SK, Clipson L, Deming DA. “Human Colon Organoids and Other Laboratory Strategies to Enhance Patient Treatment Selection.” Current Treatment Options in Oncology 21(5):35, 2020. PMID: 3232881 

Shah SI, D’Angelo CR, Kratz JD, Yang DT. “Diagnostic Challenges in an Aggressive Case of Peripheralizing Marginal Zone Lymphoma.” Clinical Case Reports 8(12):3303-3310, 2020. PMID: 33363923 

 

2019 

DeStefanis RD, Kratz JD, Emmerich PB, Deming DA. “Targeted Therapy in Metastatic Colorectal Cancer: Current Standards and Novel Agents in Review.” Current Colorectal Cancer Report 15: 61-69, 2019.PMID: 31130830 

 

2018 

Fricke SL, Payne SN, Favreau PF, Kratz JD, Pasch CA, Foley TM, Yueh AE, Van De Hey DR, Depke MG, Korkos DP, Sha GC, DeStefanis RA, Clipson L, Burkard ME, Lemmon KK, Parsons BM, Kenny PA, Matkowskyj KA, Newton MA, Skala MC, Deming DA. “MTORC1/2 inhibition as a therapeutic strategy for PIK3CA mutant cancers.” Molecular Cancer Therapeutics 18(2): 346-355, 2018. PMID: 30425131 

Kratz JD, Uboha NV, Lubner SJ, Mulkerin DL, Clipson L, Yi Y, Yu M, Matkowskyj KA, LoConte NK, Deming DA. “Metastatic bulk independently predicts outcomes for precision targeting in late-line colorectal cancer.” JNCCN 16(12): 1442-1450, 2018. PMID: 3054599  

Kratz JD, Burkard ME, O’Meara T, Pusztai, L, Veitch Z, Bedard PL. “Incorporating Genomics into the Care of Patients with Advanced Breast Cancer.” ASCO Education Book 38:56-64, 2018. PMID: 30231387 

 

2016 

Kratz JD, Chaddha A, Bhattacharjee S, Goonewardena SN. “Atherosclerosis and Nanotechnology: Diagnostic and Therapeutic Applications.” Cardiovascular Drugs and Therapy 29: 1-7, 2016. PMID: 26809711 

Sievers CK, Kratz JD, Zurbriggen LD, LoConte N, Lubner SJ, Uboha N, Mulkerin D, Matkowskyj KA, Deming DA. “The Multidisciplinary Management of Colorectal Cancer: Present and Future Paradigms.” Clinics in Colon and Rectal Surgery 29 (3): 1-7, 2016. PMID: 27582648 

Kratz JD, Turk AA, Sievers CK, Clipson L, Matkowskyj KA, Deming DA. “Molecular Profiles Guide Colorectal Cancer Treatment.” Federal Practitioner 33 (S4): 50-53, 2016. PMID: 30766219 ] 

Kratz JD, El-Shazly AY, Mambuque SG, Demetria E, Veldkamp P, Anderson TS. “Gynaecomastia in two men on stable antiretroviral therapy who commenced treatment for tuberculosis.” Malawi Medical Journal 28(4): 185–187, 2016. PMID: 28321284 

 

2013 

Goonewardena SN, Kratz JD, Zong H, Desai AM, Tang S, Emery S, Baker JR Jr, Huang B. “Design Considerations for PAMAM Dendrimer Therapeutics.” Bioorganic & Medicinal Chemistry Letters 23 (10): 2872-5, 2013. PMID: 23583511 

 

2011 

Stelzer AC, Frank, AT, Kratz JD, Swanson MD, Gonzalez-Hernandez MJ, Lee J, Andricioaei I, Markovitz DM, and Al-Hashimi HM. “Discovery of Selective Bioactive Small Molecules by Targeting an RNA Dynamic Ensemble.” Nature Chemical Biology 7(8): 553-9, 2011. PMID: 21706033 

 

2010 

Kratz JD, Stelzer AC, Zhang Q, and Al-Hashimi HM. “RNA Dynamics by Design: Biasing Ensemble Towards Ligand Bound States.” Angewandte Chemie 49(33): 5731-3, 2010 (featured on cover). PMID: 20583015